Article
Chromosome 22q allelic losses at microsatellite loci in human astrocytic tumors.
Neurologia medico-chirurgica - 1 Aug 1997
Muhammad A K, Yoshimine T, Maruno M, Tokiyoshi K, Takemoto O, Hayakawa T
Abstract excerpt
Common regions of deletion(s) on chromosome 22q and the correlations between loss of heterozygosity and patient survival were analysed in 18 deoxyribonucleic acid samples from astrocytic tumors (3 astrocytomas, 5 anaplastic astrocytomas, and 11 glioblastomas) and matched normal brain tissues. The polymerase chain reaction products using five microsatellite markers were electrophoresed on polyacrylamide gels and...
Topics
- Adult
- Aged
- Alleles
- Astrocytoma
- Brain
- Brain Neoplasms
- Child
- Chromosome Deletion
- Chromosomes, Human, Pair 22
- Female
- Glioblastoma
- Heterozygote
