Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low-level microsatellite instability phenotype in sporadic glioblastoma multiforme.

Journal of cancer research and clinical oncology - 1 Feb 2005

Martinez R, Schackert H K, Appelt H, Plaschke J, Baretton G, Schackert G

Abstract excerpt

PURPOSE: Genetic instability is a hallmark of glioblastoma multiforme (GBM). Microsatellite instability (MSI) is a significant event in the tumorigenesis of many sporadic malignancies. The aim of our investigation was to study microsatellite instability in newly diagnosed glioblastomas. METHODS: MSI was investigated in 109 GBMs with 15 microsatellite markers. Immunohistochemistry was performed for the mismatch...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pair Mismatch
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to DNA Damage

Share to DNA Repair

Share to Glioblastoma

Share to Immunohistochemistry

Share to Microsatellite Repeats

Source

Identifiers

PMID: 15672285
DOI: 10.1007/s00432-004-0592-5

Genes

EGFR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low-level microsatellite instability phenotype in sporadic glioblastoma multiforme.PMID 15672285Read ↗

Microsatellite Instability in Pediatric and Adult High‐grade GliomasSemantic proximity Read ↗

Integrated analysis of mismatch repair system in malignant astrocytomas.Semantic proximity Read ↗

Microsatellite instability and the PTEN1 gene mutation in a subset of early onset gliomas carrying germline mutation or promoter methylation of the hMLH1 gene.Semantic proximity Read ↗

Instability of microsatellites in human gliomas.Semantic proximity Read ↗

Microsatellite instability is infrequent in sporadic adult gliomas.Semantic proximity Read ↗

Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer.Semantic proximity Read ↗

hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability.Semantic proximity Read ↗

Role of the BRAF mutations in the microsatellite instability genetic pathway in sporadic colorectal cancer.Semantic proximity Read ↗

Mismatch-Repair Protein Expression in High-Grade Gliomas: A Large Retrospective Multicenter StudySemantic proximity Read ↗

Aberrant protein expression and frequent allelic loss of MSH3 in colorectal cancer with low-level microsatellite instability.Semantic proximity Read ↗

Alterations of DNA mismatch repair proteins and microsatellite instability levels in gastric cancer cell lines.Semantic proximity Read ↗

Mismatch Repair Proteins hMLH1 and hMSH2 Are Differently Expressed in the Three Main Subtypes of Sporadic Renal Cell CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.