Article
Role of genomic instability in meningioma progression.
Genes, chromosomes & cancer - 1 Aug 1996
Simon M, Kokkino A J, Warnick R E, Tew J M, von Deimling A, Menon A G
Abstract excerpt
Microsatellite length instability, probably resulting from defective DNA mismatch repair mechanisms, has been described in a variety of cancers. Such genetic instability may play a significant role in tumor formation and progression. To investigate the role of microsatellite alterations in meningioma tumorigenesis and progression, we examined 33 microsatellite markers on nine chromosomes for abnormalities in 18...
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