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Article

Role of genomic instability in meningioma progression.

Genes, chromosomes & cancer - 1 Aug 1996

Simon M, Kokkino A J, Warnick R E, Tew J M, von Deimling A, Menon A G

Abstract excerpt

Microsatellite length instability, probably resulting from defective DNA mismatch repair mechanisms, has been described in a variety of cancers. Such genetic instability may play a significant role in tumor formation and progression. To investigate the role of microsatellite alterations in meningioma tumorigenesis and progression, we examined 33 microsatellite markers on nine chromosomes for abnormalities in 18...

Topics

Alleles
Chromosomes, Human
Humans
Meningioma
Microsatellite Repeats
Mutagenesis
Sequence Deletion

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8875241
DOI: 10.1002/(SICI)1098-2264(199608)16:4<265::AID-GCC7>3.0.CO;2-W

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