Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins.

doi:10.1006/viro.1995.1072

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Article

Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins.

Virology - 20 Feb 1995

Yang Q, Chen F, Ross J, Trempe J P

Abstract excerpt

In order to define the mechanism used by the adeno-associated virus replication (rep) gene to mediate inhibition of cell proliferation, we have studied its effects on SV40 and cellular DNA replication. SV40 DNA replication was inhibited by the presence of the rep gene in human 293 cells, and the...

Topics

3T3 Cells
Animals
Antigens, Viral, Tumor
Cell Line
DNA Replication
DNA-Binding Proteins
Dependovirus
Gene Expression Regulation, Viral
Genes, Viral
Humans
Mice
Mutation
Simian virus 40
Viral Proteins
Virus Replication

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