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Article

Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins.

Virology - 20 Feb 1995

Yang Q, Chen F, Ross J, Trempe J P

Abstract excerpt

In order to define the mechanism used by the adeno-associated virus replication (rep) gene to mediate inhibition of cell proliferation, we have studied its effects on SV40 and cellular DNA replication. SV40 DNA replication was inhibited by the presence of the rep gene in human 293 cells, and the inhibition was not linked to suppression of SV40 early gene expression. Using double-immunofluorescence assays that...

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Identifiers

PMID: 7871734
DOI: 10.1006/viro.1995.1072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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