Article
Modulation of the cellular phenotype by integrated adeno-associated virus.
Virology - 1 Sept 1992
Winocour E, Puzis L, Etkin S, Koch T, Danovitch B, Mendelson E, Shaulian E, Karby S, Lavi S
Abstract excerpt
The adeno-associated virus (AAV) rep gene encodes a series of overlapping, multifunctional, nonstructural proteins (Rep proteins) which regulate the viral life cycle and which are also capable of trans-regulating nonviral gene expressions (reviewed in Berns, 1990, Microbiol. Rev. 54, 316-329). To investigate the expression of the AAV rep gene in a cellular chromosomal context, SV40-transformed Chinese hamster...
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