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Article

Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels.

Journal of virology - 1 May 1994

Kyöstiö S R, Owens R A, Weitzman M D, Antoni B A, Chejanovsky N, Carter B J

Abstract excerpt

The rep gene of adeno-associated virus type 2 (AAV) encodes four overlapping Rep proteins that are involved in gene regulation and replication of the virus. We studied here the regulation of mRNA transcribed from the AAV p5 and p19 promoters, using transient expression in human 293 cells followed by Northern (RNA) blot analysis of the mRNA. The p5 transcript encodes the larger Rep proteins, Rep78 and Rep68, while...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8151765
DOI: 10.1128/JVI.68.5.2947-2957.1994
PMCID: PMC236783

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Source receipt: pubmed, retrieved 7 Sept 2026.

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