Article
Adeno-associated virus type 2 Rep40 modulates the proliferation rate of Rep52-expressing HeLa cells.
Intervirology - 1 Jan 2003
Li Donglan, Kashii Saburo, Sahara Toshiyuki, Ito Kazuhiko
Abstract excerpt
OBJECTIVE: To investigate the growth-inhibitory effect of Rep proteins on cells. METHODS: We generated Rep-expressing plasmids that containing wild-type rep genes or mutant rep genes with point mutations in their ATP-binding sites. We obtained several HeLa cell clones expressing Rep proteins constitutively by the regulator plasmid. The expression of each Rep protein was detected by Western blotting with an...
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