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Article

Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters

1 Sept 1995

Abstract excerpt

The four Rep proteins encoded by adeno-associated virus type 2 (AAV-2) inhibit transcription of their own promoters and of several heterologous promoters. To gain insight into the molecular mechanism of Rep-mediated transcription repression, we studied the effects of the four Rep proteins on the accumulation of mRNA transcribed from the human papillomavirus type 18 upstream regulatory region HPV18 URR, the human...

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PMID: 7636994
DOI: 10.1128/jvi.69.9.5485-5496.1995

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Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promotersPMID 7636994Read ↗

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