Article
Interlaboratory comparison: liver spontaneous mutant frequency from lambda/lacI transgenic mice (Big Blue) (II).
Mutation research - 1 Mar 1995
Young R R, Rogers B J, Provost G S, Short J M, Putman D L
Abstract excerpt
Spontaneous mutant frequency in livers of two transgenic mouse strains, each carrying identical lambda shuttle vectors with a lacI target gene, was evaluated by two laboratories. These studies investigated variability in spontaneous mutant frequency between animals and as a function of the number of phage screened. Liver DNA was independently isolated from 7-11 week old C57BL/6 and B6C3F1 Big Blue transgenic...
Topics
- Animals
- Bacterial Proteins
- Chromogenic Compounds
- DNA, Recombinant
- Enzyme Induction
- Escherichia coli
- Escherichia coli Proteins
- Female
- Galactosides
- Gene Expression Regulation, Bacterial
- Genes, Reporter
