Comparison of lacI and lacZ transgenic mouse mutation assays: an EU-sponsored interlaboratory study.

doi:10.1016/0165-1161(95)90054-3

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Article

Comparison of lacI and lacZ transgenic mouse mutation assays: an EU-sponsored interlaboratory study.

Mutation research - 1 Oct 1995

Tinwell H, Liegibel U, Krebs O, Schmezer P, Favor J, Ashby J

Abstract excerpt

As part of an EU Environment Programme sponsored study, the performance of two transgenic mouse mutation assays has been evaluated in three laboratories using common liver samples. The systems studied were the lacI-(Big Blue) mutation assay, and the GalE- positive selection modified lacZ- (Muta M...

Topics

Animals
DNA
Dimethylnitrosamine
Evaluation Studies as Topic
Laboratories
Lac Operon
Liver
Mice
Mice, Transgenic
Mutagenicity Tests
Mutation

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