Article
Comparison of lacI and lacZ transgenic mouse mutation assays: an EU-sponsored interlaboratory study.
Mutation research - 1 Oct 1995
Tinwell H, Liegibel U, Krebs O, Schmezer P, Favor J, Ashby J
Abstract excerpt
As part of an EU Environment Programme sponsored study, the performance of two transgenic mouse mutation assays has been evaluated in three laboratories using common liver samples. The systems studied were the lacI-(Big Blue) mutation assay, and the GalE- positive selection modified lacZ- (Muta Mouse) assay. The liver samples compared were derived from mice treated with either saline or dimethylnitrosamine (DMN;...
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