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Article

The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology.

Nature genetics - 1 Oct 2004

Freimer Nelson, Sabatti Chiara

Abstract excerpt

Efforts to identify gene variants associated with susceptibility to common diseases use three approaches: pedigree and affected sib-pair linkage studies and association studies of population samples. The different aims of these study designs reflect their derivation from biological versus epidemiological traditions. Similar principles regarding determination of the evidence levels required to consider the results...

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PMID: 15454942
DOI: 10.1038/ng1433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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