Article
Mutations of the Ki-ras oncogene in carcinoma of the endometrium.
The American journal of pathology - 1 Jan 1995
Caduff R F, Johnston C M, Frank T S
Abstract excerpt
Mutations of the Ki-ras oncogene in endometrial carcinoma have been reported in Japan, but the prevalence and clinical significance of such mutations in the United States remains unclear. DNA extracted from paraffin sections of 112 carcinomas of the endometrium was amplified by the polymerase chain reaction with mismatched primers that generated a BstNI recognition site with the wild-type codon 12. Loss of this...
Topics
- Adenocarcinoma
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- Carcinosarcoma
- DNA, Neoplasm
- Endometrial Neoplasms
- Female
- Genes, ras
- Humans
- Middle Aged
