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Article

p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.

Cancer research - 1 Jul 1993

Teneriello M G, Ebina M, Linnoila R I, Henry M, Nash J D, Park R C, Birrer M J

Abstract excerpt

In an effort to define the pathogenic relationship between ovarian neoplasms spanning the clinicopathological spectrum from benign to malignant, the incidence of Ki-ras and p53 mutations was determined in 20 ovarian cystadenomas, 20 low malignant potential (LMP) tumors of the ovary, and 23 ovarian carcinomas. Using DNA extracted from paraffin embedded tissue, polymerase chain reaction amplification, designed...

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PMID: 8319218

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