Article
K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary.
The American journal of pathology - 1 Oct 1991
Enomoto T, Weghorst C M, Inoue M, Tanizawa O, Rice J M
Abstract excerpt
To explore the role of mutational activation of members of the ras family of cellular protooncogenes in the development of human ovarian neoplasms, a series of 37 ovarian tumors from Japanese patients was studied. These included 30 common epithelial tumors (1 mucinous tumor of borderline malignan...
Topics
- Adenocarcinoma, Mucinous
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- DNA, Neoplasm
- Female
- Gene Amplification
- Gene Expression Regulation, Neoplastic
- Genes, ras
- Humans
- Japan
- Middle Aged
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Ovarian Neoplasms