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Article

K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary.

The American journal of pathology - 1 Oct 1991

Enomoto T, Weghorst C M, Inoue M, Tanizawa O, Rice J M

Abstract excerpt

To explore the role of mutational activation of members of the ras family of cellular protooncogenes in the development of human ovarian neoplasms, a series of 37 ovarian tumors from Japanese patients was studied. These included 30 common epithelial tumors (1 mucinous tumor of borderline malignancy, 7 mucinous adenocarcinomas, and 22 nonmucinous carcinomas: 10 serous, 3 clear cell, 8 endometrioid, and 1...

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Identifiers

PMID: 1656759
PMCID: PMC1886299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary.PMID 1656759Read ↗

Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy.Semantic proximity Read ↗

k-ras mutation may be an early event in mucinous ovarian tumorigenesis.Semantic proximity Read ↗

K-ras mutations in mucinous ovarian tumorsSemantic proximity Read ↗

Endometrial carcinomas with significant mucinous differentiation associated with higher frequency of k-ras mutations: a morphologic and molecular correlation study.Semantic proximity Read ↗

Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms.Semantic proximity Read ↗

p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.Semantic proximity Read ↗

Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients.Semantic proximity Read ↗

Oncogenesis in ovarian cancer.Semantic proximity Read ↗

Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms.Semantic proximity Read ↗

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