K-ras activation in premalignant and malignant epithelial lesions of the human uterus.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

K-ras activation in premalignant and malignant epithelial lesions of the human uterus.

Cancer research - 1 Oct 1991

Enomoto T, Inoue M, Perantoni A O, Buzard G S, Miki H, Tanizawa O, Rice J M

Abstract excerpt

We previously reported (Cancer Res., 50:6139-6145, 1990) a significant frequency of activating point mutations in codon 12 of the K-ras oncogene in endometrial adenocarcinomas of the uterine corpus (series 1). To further define the role of ras activation in the development of endometrial adenocarcinoma, we surveyed cystic, adenomatous, and atypical hyperplasias of uterine endometrium and additional cases of...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Base Sequence
Blotting, Southern
Epithelium
Female
Gene Expression
Genes, ras
Humans
Hyperplasia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Molecular Sequence Data

Mutation

Polymerase Chain Reaction

Precancerous Conditions

Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 1913654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1913654-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

K-ras activation in premalignant and malignant epithelial lesions of the human uterus.PMID 1913654Read ↗

Mutation of the Ki-ras protooncogene in human endometrial hyperplasia and carcinoma.Semantic proximity Read ↗

K-ras activation in neoplasms of the human female reproductive tract.Semantic proximity Read ↗

Alteration of the p53 tumor suppressor gene and activation of c-K-ras-2 protooncogene in endometrial adenocarcinoma from Colorado.Semantic proximity Read ↗

Analysis of oncogene alterations in human endometrial carcinoma: prevalence of ras mutations.Semantic proximity Read ↗

K-ras mutation in tamoxifen-related endometrial polyps.Semantic proximity Read ↗

Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma.Semantic proximity Read ↗

K‐<i>ras</i> codon 12 mutations in Barrett’s oesophagus and adenocarcinomas of the oesophagus and oesophagogastric junctionSemantic proximity Read ↗

Mutations of the KRAS oncogene in endometrial hyperplasia and carcinoma.Semantic proximity Read ↗

Clinical implications of K-ras mutations in malignant epithelial tumors of the endometrium.Semantic proximity Read ↗

Clinical significance of ras oncogene activation in human lung cancer.Semantic proximity Read ↗

K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary.Semantic proximity Read ↗

Detection of c-Ki-ras gene mutation in paraffin sections of adenocarcinoma and atypical bronchioloalveolar cell hyperplasia of human lung.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.