Article
Clinical implications of K-ras mutations in malignant epithelial tumors of the endometrium.
Cancer research - 15 May 1992
Mizuuchi H, Nasim S, Kudo R, Silverberg S G, Greenhouse S, Garrett C T
Abstract excerpt
Tumorigenesis in humans and experimental animals appears to involve the activation of ras protooncogenes for a number of organ systems and seems to be important to the development of the metastatic phenotype in several model systems. Clinically, the presence of activated ras protooncogenes has been reported to be a negative prognostic factor in the myelodysplastic syndrome and in adenocarcinoma of the lung. In...
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