Clinical implications of K-ras mutations in malignant epithelial tumors of the endometrium.

Article

Clinical implications of K-ras mutations in malignant epithelial tumors of the endometrium.

Cancer research - 15 May 1992

Mizuuchi H, Nasim S, Kudo R, Silverberg S G, Greenhouse S, Garrett C T

Abstract excerpt

Tumorigenesis in humans and experimental animals appears to involve the activation of ras protooncogenes for a number of organ systems and seems to be important to the development of the metastatic phenotype in several model systems. Clinically, the presence of activated ras protooncogenes has be...

Topics

Base Sequence
Endometrial Neoplasms
Epithelium
Exons
Female
Genes, ras
Humans
Lymph Nodes
Molecular Sequence Data
Multivariate Analysis
Mutation
Polymerase Chain Reaction
Prognosis
Proportional Hazards Models

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