Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma.

Article

Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma.

Cancer research - 15 Mar 1994

Duggan B D, Felix J C, Muderspach L I, Tsao J L, Shibata D K

Abstract excerpt

Endometrial carcinoma is theorized to arise from a series of somatic mutations which alter benign endometrium to progressively less differentiated histological lesions. One genetic alteration implicated in the carcinogenesis of endometrial cancer is the mutational activation of the c-Ki-ras oncog...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Alleles
Endometrial Neoplasms
Female
Gene Expression Regulation, Neoplastic
Genes, ras
Humans
Middle Aged
Point Mutation

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