Article
Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma.
Cancer research - 15 Mar 1994
Duggan B D, Felix J C, Muderspach L I, Tsao J L, Shibata D K
Abstract excerpt
Endometrial carcinoma is theorized to arise from a series of somatic mutations which alter benign endometrium to progressively less differentiated histological lesions. One genetic alteration implicated in the carcinogenesis of endometrial cancer is the mutational activation of the c-Ki-ras oncogene. This study characterizes the frequency and the topographical distribution of activated c-Ki-ras alleles in...
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