Article
Molecular characterization of eukaryotic polysialyltransferase-1.
Nature - 23 Feb 1995
Eckhardt M, Mühlenhoff M, Bethe A, Koopman J, Frosch M, Gerardy-Schahn R
Abstract excerpt
Polysialic acid (PSA) is a dynamically regulated product of post-translational modification of the neural cell adhesion molecule, NCAM. Presence of the large anionic carbohydrate modulates NCAM binding properties and, by increasing the intercellular space, influences interactions between other ce...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- CHO Cells
- Cell Adhesion Molecules, Neuronal
- Cell Line
- Cloning, Molecular
- Cricetinae
- DNA, Complementary
- Mice
- Molecular Sequence Data
- Mutation
- Plasmids
- Sialic Acids
- Sialyltransferases