Article
Mutants of Escherichia coli with increased fidelity of DNA replication.
Genetics - 1 Aug 1993
Fijalkowska I J, Dunn R L, Schaaper R M
Abstract excerpt
To improve our understanding of the role of DNA replication fidelity in mutagenesis, we undertook a search for Escherichia coli antimutator strains with increased fidelity of DNA replication. The region between 4 and 5 min of the E. coli chromosome was mutagenized using localized mutagenesis mediated by bacteriophage P1. This region contains the dnaE and dnaQ genes, which encode, respectively, the DNA polymerase...
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