Article
Spontaneous mutation in the Escherichia coli lacI gene.
Genetics - 1 Oct 1991
Schaaper R M, Dunn R L
Abstract excerpt
To gain more detailed insight into the nature and mechanisms of spontaneous mutations, we undertook a DNA sequence analysis of a large collection of spontaneous mutations in the N-terminal region of the Escherichia coli lacI gene. This region of circa 210 base pairs is the target for dominant lacI mutations (i-d) and is suitable for studies of mutational specificity since it contains a relatively high density of...
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