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Article

Genetic evidence for difference between intracellular and extracellular peptides in influenza A matrix peptide-specific CTL recognition.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1995

Matsui M, Moots R J, Warburton R J, Peace-Brewer A L, Tussey L G, Quinn D G, McMichael A J, Frelinger J A

Abstract excerpt

During the course of extensive mutagenesis of HLA-A2.1, we examined influenza A matrix peptide (FMP)-specific CTL recognition of HMy2.C1R (C1R) cells expressing mutant HLA-A2.1 molecules, sensitized with synthetic peptide, FMP 58-66, (exogenous peptide), or infected with influenza A virus (endogenous peptide). Most mutants showed equivalent presentation of exogenous and endogenous peptides to FMP-specific CTL....

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PMID: 7822785

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Genetic evidence for difference between intracellular and extracellular peptides in influenza A matrix peptide-specific CTL recognition.PMID 7822785Read ↗

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