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Article

The 45 pocket of HLA-A2.1 plays a role in presentation of influenza virus matrix peptide and alloantigens.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 1991

Winter C C, Carreno B M, Turner R V, Koenig S, Biddison W E

Abstract excerpt

Amino acid substitutions were introduced into the 45 pocket of HLA-A2.1 to determine the potential role of this structurally defined feature of class I molecules in viral peptide and alloantigen presentation. The 45 pocket lies below the alpha 1-domain alpha-helix and is composed of five amino acids, three of which differ between HLA-A2.1 and HLA-B37. These two class I molecules have previously been shown to have...

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PMID: 2026879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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