The 45 pocket of HLA-A2.1 plays a role in presentation of influenza virus matrix peptide and alloantigens.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The 45 pocket of HLA-A2.1 plays a role in presentation of influenza virus matrix peptide and alloantigens.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 1991

Winter C C, Carreno B M, Turner R V, Koenig S, Biddison W E

Abstract excerpt

Amino acid substitutions were introduced into the 45 pocket of HLA-A2.1 to determine the potential role of this structurally defined feature of class I molecules in viral peptide and alloantigen presentation. The 45 pocket lies below the alpha 1-domain alpha-helix and is composed of five amino ac...

Topics

Base Sequence
Gene Products, tax
HLA-A Antigens
Humans
Influenza A virus
Isoantigens
Models, Molecular
Molecular Sequence Data
Mutation
Structure-Activity Relationship
T-Lymphocytes, Cytotoxic
Transfection
Viral Matrix Proteins

Source

Open in PubMed

Identifiers

PMID: 2026879

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2026879-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics