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Article

Aberrant rearrangements within the immunoglobulin heavy chain locus in hairy cell leukemia.

Leukemia & lymphoma - 1 Jan 1994

Kayano H, Dyer M J, Zani V J, Laffan M A, Matutes E, Asou N, Katayama I, Catovsky D

Abstract excerpt

The cell surface expression of multiple immunoglobulin heavy chain (IGH) isotypes, preferentially observed in hairy cell leukemia (HCL), is incompatible with the deletion model of IGH class switching, and alternative models involving RNA-splicing have been proposed. To help discriminate between these possibilities we have examined the configuration of the IGH locus by DNA blot in 38 cases of HCL. Deletion of at...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7820052

Genes

IGH
BCL2
BCL3
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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