Article
Immunophenotypic features and configuration of immunoglobulin genes in hairy cell leukemia-Japanese variant.
Leukemia - 1 Aug 1996
Yamaguchi M, Machii T, Shibayama H, Tokumine Y, Hara J, Yutsudo M, Yamada O, Klobeck H G, Kitani T
Abstract excerpt
Immunophenotypes and Ig gene rearrangements were investigated in 12 patients with a variant form of hairy cell leukemia (HCL) termed HCL-Japanese variant (HCL-J), and in an HCL-J-derived cell line. The leukemic cells of HCL-J characteristically showed the phenotype of CD20+, CD5-, CD10-, CD11c+, CD22+, CD24- and CD25-. Ig light (L) chain was undetected in nine cases, and the remaining four cases expressed kappa...
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