Article
Hairy cell leukemia has a B-cell genotype.
Hematological oncology - 1 Jan 2000
Meyers F J, Cardiff R D, Taylor C R, Zuniga M, Radich J
Abstract excerpt
The phenotype and, by inference, the cell of origin of some lymphocytic neoplasms has been defined by surface marker studies; however, the precise cellular origin of other neoplasms of the lymphoid system is still unknown. For example, with reference to hairy cell leukemia (HCL), cell marker data has been used in support of a monocytic, a T cell, or a B cell origin. If hairy cell leukemia is a B cell-derived...
Topics
- B-Lymphocytes
- Base Sequence
- DNA, Neoplasm
- Genes
- Genotype
- Humans
- Immunoglobulin J-Chains
- Leukemia, Hairy Cell
- Nucleic Acid Hybridization