Article
Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus.
Tissue antigens - 1 Feb 1995
Sanjeevi C B, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark A
Abstract excerpt
Analysis of HLA-DQ molecules in a large study comprising 425 consecutively diagnosed Swedish Caucasians with IDDM and 367 age, sex and geographically matched controls confirms previous observations that: (a) DQB1*0302-DQA1*0301 confer susceptibility in a dominant manner, except when they are asso...
Topics
- Adolescent
- Alleles
- Case-Control Studies
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Genes, Dominant
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Haplotypes
- Humans
- Infant
- Infant, Newborn
- Polymerase Chain Reaction