Article
The interaction between the first and last intron nucleotides in the second step of pre-mRNA splicing is independent of other conserved intron nucleotides.
Nucleic acids research - 11 Dec 1994
Ruis B L, Kivens W J, Siliciano P G
Abstract excerpt
Virtually all pre-mRNA introns begin with the sequence /GU and end with AG/ (where / indicates a border between an exon and an intron). We have previously shown that the G residues at the first and last positions of the yeast actin intron interact during the second step of splicing. In this work, we ask if other highly conserved intron nucleotides also take part in this /G-G/ interaction. Of special interest is...
Topics
- Base Sequence
- Conserved Sequence
- DNA, Recombinant
- Introns
- Molecular Sequence Data
- Mutation
- RNA Precursors
- RNA Splicing
- RNA, Fungal
- Ribonucleotides
- Yeasts