Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron.

doi:10.1038/361660a0

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Article

Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron.

Nature - 18 Feb 1993

Parker R, Siliciano P G

Abstract excerpt

Nuclear pre-messenger RNA splicing requires the action of five small nuclear (sn) RNAs, U1, U2, U4, U5 and U6, and more than 50 proteins. The mechanistic similarity of nuclear pre-mRNA splicing and group II self-splicing suggests that many of the central processes of nuclear pre-mRNA splicing are...

Topics

Base Composition
Base Sequence
Binding Sites
Exons
Introns
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA Precursors
RNA Splicing
RNA, Fungal
RNA, Messenger
Saccharomyces cerevisiae
beta-Galactosidase

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