Gain-of-function mutations conferring actin-severing activity to human macrophage cap G.

doi:10.1074/jbc.270.1.45

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Article

Gain-of-function mutations conferring actin-severing activity to human macrophage cap G.

The Journal of biological chemistry - 6 Jan 1995

Southwick F S

Abstract excerpt

Nonmuscle cell motility requires marked changes in the consistency and shape of the peripheral cytoplasm. These changes are regulated by a gel-sol transformation of the actin filament network, and actin filament-severing proteins are responsible for network solation. Macrophage Cap G, unlike all...

Topics

Actins
Amino Acid Sequence
Humans
Macrophages
Microfilament Proteins
Molecular Sequence Data
Mutation
Nuclear Proteins
Sequence Homology, Amino Acid
Structure-Activity Relationship

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