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Article

Chimeric and truncated gCap39 elucidate the requirements for actin filament severing and end capping by the gelsolin family of proteins.

The Journal of biological chemistry - 15 Oct 1991

Yu F X, Zhou D M, Yin H L

Abstract excerpt

gCap39 is an actin filament end-capping protein which has a threefold repeated domain structure similar to the N-terminal half of gelsolin. However, unlike gelsolin, gCap39 does not sever actin filaments and dissociates completely from filament ends after calcium removal. We have capitalized on these differences to explore the structural basis for actin filament capping, severing, and their regulation. Using...

Topics

Actins
Base Sequence
Calcium
Calcium-Binding Proteins
Chimera
Chymotrypsin
Electrophoresis, Polyacrylamide Gel
Gelsolin
Hydrolysis
Microfilament Proteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nerve Tissue Proteins

Nuclear Proteins

Restriction Mapping

Spectrometry, Fluorescence

Source

Identifiers

PMID: 1655780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1655780-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Chimeric and truncated gCap39 elucidate the requirements for actin filament severing and end capping by the gelsolin family of proteins.PMID 1655780Read ↗

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