Article
Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin.
Journal of cell science - 1 Dec 2014
Zhou Guo-Lei, Zhang Haitao, Wu Huhehasi, Ghai Pooja, Field Jeffrey
Abstract excerpt
Cell signaling can control the dynamic balance between filamentous and monomeric actin by modulating actin regulatory proteins. One family of actin regulating proteins that controls actin dynamics comprises cyclase-associated proteins 1 and 2 (CAP1 and 2, respectively). However, cell signals that regulate CAPs remained unknown. We mapped phosphorylation sites on mouse CAP1 and found S307 and S309 to be regulatory...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
