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Article

Differential expression of GABAA receptor subunit mRNAs in ethanol-naive withdrawal seizure resistant (WSR) vs. withdrawal seizure prone (WSP) mouse brain.

Brain research. Molecular brain research - 1 Sept 1994

Keir W J, Morrow A L

Abstract excerpt

Several lines of evidence suggest an important role for ethanol interactions with GABAA receptors in the development of the ethanol withdrawal syndrome. The present study was undertaken to determine whether there is a genetic relationship between ethanol withdrawal seizure severity and the expression of particular GABAA receptor subunits in mouse lines selectively bred for differential sensitivity to ethanol...

Topics

Animals
Brain
Cerebellum
Cerebral Cortex
Ethanol
Genetic Predisposition to Disease
Mice
Mice, Inbred Strains
RNA, Messenger
Receptors, GABA-A
Seizures

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Substance Withdrawal Syndrome

Source

Identifiers

PMID: 7808218
DOI: 10.1016/0169-328x(94)90154-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7808218-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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