Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Indexing withdrawal in mice: matching genotypes for exposure in studies using ethanol vapor inhalation.

Alcoholism, clinical and experimental research - 1 Jun 1994

Terdal E S, Crabbe J C

Abstract excerpt

Withdrawal Seizure-Prone (WSP) and -Resistant (WSR) mice have been bidirectionally selected for severity of handling-induced convulsions (HIC) following withdrawal from 72 hr of chronic ethanol vapor inhalation. During selection, daily injections of the alcohol dehydrogenase inhibitor, pyrazole, were used to enhance and stabilize blood ethanol concentrations (BEC). After 26 generations of selection, WSR mice show...

Topics

Administration, Inhalation
Alcohol Dehydrogenase
Alcohol Withdrawal Delirium
Animals
Dose-Response Relationship, Drug
Ethanol
Genotype
Handling, Psychological
Mice
Mice, Inbred Strains
Pyrazoles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Seizures

Selection, Genetic

Source

Identifiers

PMID: 7943652
DOI: 10.1111/j.1530-0277.1994.tb00907.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7943652-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Indexing withdrawal in mice: matching genotypes for exposure in studies using ethanol vapor inhalation.PMID 7943652Read ↗

Chronic ethanol differentially alters susceptibility to chemically induced convulsions in withdrawal seizure-prone and -resistant mice.Semantic proximity Read ↗

Regulation of operant ethanol-reinforced behavior is genetically independent of regulation of withdrawal severity in WSP and WSR mice.Semantic proximity Read ↗

Use of a novel mouse genotype to model acute benzodiazepine withdrawal.Semantic proximity Read ↗

Selective breeding for alcohol withdrawal severity.Semantic proximity Read ↗

Ethanol reward and aversion in mice bred for sensitivity to ethanol withdrawal.Semantic proximity Read ↗

Ethanol Tolerance and Withdrawal Severity in High Drinking in the Dark Selectively Bred MiceSemantic proximity Read ↗

Anxiety and sensitivity to ethanol and pentobarbital in alcohol withdrawal seizure-prone and withdrawal seizure-resistant mice.Semantic proximity Read ↗

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.Semantic proximity Read ↗

Selective breeding for ethanol-related traits alters circadian phenotype.Semantic proximity Read ↗

Escalation of intake under intermittent ethanol access in diverse mouse genotypes.Semantic proximity Read ↗

Genetic and pharmacological manipulations of glyoxalase 1 mediate ethanol withdrawal seizure susceptibility in miceSemantic proximity Read ↗

Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.