Ethanol-regulated gene expression of neuroendocrine specific protein in mice: brain region and genotype specificity.

doi:10.1016/s0006-8993(01)02110-2

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Article

Ethanol-regulated gene expression of neuroendocrine specific protein in mice: brain region and genotype specificity.

Brain research - 6 Apr 2001

Schafer G L, Crabbe J C, Wiren K M

Abstract excerpt

Neuroendocrine specific protein or reticulon 1 (NSP/RTN1) was identified as a putative ethanol-regulated gene using mRNA differential display in mice genetically selected for severe ethanol withdrawal (withdrawal seizure-prone, WSP). One transcript of RTN1 (3.0 kb) showed a statistically significant increase (13%) in relative abundance in whole brain of ethanol-treated WSP mice but not in mice selected for...

Topics

Alcohol Withdrawal Seizures
Alcoholism
Animals
Behavior, Animal
Blotting, Northern
Brain Chemistry
Central Nervous System Depressants
Cerebellum
Cerebral Cortex
Ethanol
Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Hippocampus

Male

Mice

Mice, Inbred C57BL

Mice, Inbred DBA

Mice, Mutant Strains

Source

Open in PubMed

Identifiers

PMID: 11282367
DOI: 10.1016/s0006-8993(01)02110-2

Genes

RTN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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