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Article

Regulation of operant ethanol-reinforced behavior is genetically independent of regulation of withdrawal severity in WSP and WSR mice.

Alcohol (Fayetteville, N.Y.) - 1 Jan 2000

Barbera T J, Baca K, George F R

Abstract excerpt

Selectively bred withdrawal seizure prone (WSP1 and WSP2) and withdrawal seizure resistant (WSR1 and WSR2) mice were used to test the extent to which severity of ethanol withdrawal response is predictive of the reinforcing effects of ethanol. Mice were systematically introduced to ethanol under a fixed ratio 1 (FR 1) schedule using adjunctive drinking methods. There were no significant differences in ethanol...

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PMID: 7818794
DOI: 10.1016/0741-8329(94)90020-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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