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Article

An XPG DNA repair defect causing mutagen hypersensitivity in mouse leukemia L1210 cells.

Molecular and cellular biology - 1 Jan 1995

Vilpo J A, Vilpo L M, Szymkowski D E, O'Donovan A, Wood R D

Abstract excerpt

One of the most widely used antitumor drugs is cis-diamminedichloroplatinum(II) (cisplatin), and mechanisms of cisplatin resistance have been investigated in numerous model systems. Many studies have used mouse leukemia L1210/0 as a reference wild-type cell line, and cisplatin-resistant subclones have been derived from it. Increased DNA excision repair capacity is thought to play a key role in the acquired...

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Identifiers

PMID: 7799936
DOI: 10.1128/MCB.15.1.290
PMCID: PMC231955

Genes

ERCC5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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