Article
Gin mutants that can be suppressed by a Fis-independent mutation.
Journal of bacteriology - 1 Jan 1995
Spaeny-Dekking L, Schlicher E, Franken K, van de Putte P, Goosen N
Abstract excerpt
The Gin invertase of bacteriophage Mu mediates recombination between two inverted gix sites. Recombination requires the presence of a second protein, Fis, which binds to an enhancer sequence. We have isolated 24 different mutants of Gin that are impaired in DNA inversion but proficient in DNA binding. Six of these mutants could be suppressed for inversion by introduction of a second mutation, which when present...
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