Article
Analysis of strand exchange and DNA binding of enhancer-independent Gin recombinase mutants.
The EMBO journal - 1 Mar 1993
Klippel A, Kanaar R, Kahmann R, Cozzarelli N R
Abstract excerpt
The Gin recombination system of phage Mu mediates inversion of the DNA sequence between two sites (gix). In addition to Gin protein and gix sites, recombination requires an enhancer bound by the host factor FIS. We analyzed mutants of Gin that function in the absence of the enhancer and FIS and m...
Topics
- Bacteriophage mu
- Binding Sites
- DNA Nucleotidyltransferases
- DNA Topoisomerases, Type I
- DNA, Viral
- Enhancer Elements, Genetic
- Mutation
- Nucleic Acid Conformation
- Phenotype
- Recombination, Genetic