Article
Processive recombination by wild-type gin and an enhancer-independent mutant. Insight into the mechanisms of recombination selectivity and strand exchange.
Journal of molecular biology - 28 Oct 1994
Crisona N J, Kanaar R, Gonzalez T N, Zechiedrich E L, Klippel A, Cozzarelli N R
Abstract excerpt
The Gin recombinase of phage Mu selectively mediates DNA inversion between two inversely oriented recombination sites (gix) and requires the assistance of three accessory factors: negative supercoiling, an enhancer sequence, and the protein Fis. Deletion and fusion reactions are proscribed. Recom...
Topics
- Binding Sites
- Carrier Proteins
- Chromosome Inversion
- DNA Nucleotidyltransferases
- DNA, Superhelical
- DNA, Viral
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- Factor For Inversion Stimulation Protein
- Integration Host Factors
- Models, Genetic
- Mutation
- Nucleic Acid Conformation
- Recombination, Genetic