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Article

The Hin dimer interface is critical for Fis-mediated activation of the catalytic steps of site-specific DNA inversion.

Current biology : CB - 1 Feb 1996

Haykinson M J, Johnson L M, Soong J, Johnson R C

Abstract excerpt

BACKGROUND: Hin is a member of an extended family of site-specific recombinases--the DNA invertase/resolvase family--that catalyze inversion or deletion of DNA. DNA inversion by Hin occurs between two recombination sites and requires the regulatory protein Fis, which associates with a cis-acting recombinational enhancer sequence. Hin recombinase dimers bind to the two recombination sites and assemble onto the...

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PMID: 8673463
DOI: 10.1016/s0960-9822(02)00449-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Hin dimer interface is critical for Fis-mediated activation of the catalytic steps of site-specific DNA inversion.PMID 8673463Read ↗

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