Article
Cooperative binding of Tn3 resolvase monomers to a functionally asymmetric binding site.
Current biology : CB - 1 Sept 1995
Blake D G, Boocock M R, Sherratt D J, Stark W M
Abstract excerpt
BACKGROUND: The inverted repeat is a common feature of protein-binding sites in DNA. The two-fold symmetry of the inverted repeat corresponds to the two-fold symmetry of the protein that binds to it. In most natural inverted-repeat binding sites, however, the DNA sequence does not have perfect two-fold symmetry. Our study of how a site-specific recombinase recognizes an inverted-repeat binding site indicates that...
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