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Article

Gamma integrase complementation at the level of DNA binding and complex formation.

Journal of bacteriology - 1 Mar 2002

Nunes-Düby Simone E, Radman-Livaja Marta, Kuimelis Robert G, Pearline Rachel V, McLaughlin Larry W, Landy Arthur

Abstract excerpt

Site-specific recombinases of the gamma Int family carry out two single-strand exchanges by binding as head-to-head dimers on inverted core-type DNA sites. Each protomer may cleave its own site as a monomer in cis (as for Cre recombinase), or it may recruit the tyrosine from its partner in trans to form a composite active site (as for Flp recombinase). The crystal structure of the gamma Int catalytic domain is...

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Share to Bacteriophage lambda
Share to Binding Sites

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genetic Complementation Test

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Share to Recombination, Genetic

Source

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Identifiers

PMID: 11844768
DOI: 10.1128/JB.184.5.1385-1394.2002
PMCID: PMC134844

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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