Article
New mobile gene cassettes containing an aminoglycoside resistance gene, aacA7, and a chloramphenicol resistance gene, catB3, in an integron in pBWH301.
Antimicrobial agents and chemotherapy - 1 Mar 1995
Bunny K L, Hall R M, Stokes H W
Abstract excerpt
The multidrug resistance plasmid pBWH301 was shown to contain a sull-associated integron with five inserted gene cassettes, aacA7-catB3-aadB-oxa2-orfD, all of which can be mobilized by the integron-encoded DNA integrase. The aadB, oxa2, and orfD cassettes are identical to known cassettes. The aacA7 gene encodes a protein that is a member of one of the three known families of aminoglycoside acetyltransferases...
Topics
- Acetyltransferases
- Amino Acid Sequence
- Aminoglycosides
- Anti-Bacterial Agents
- Base Sequence
- Chloramphenicol Resistance
- Drug Resistance, Microbial
- Genes, Bacterial
- Molecular Sequence Data
- Phenotype