Article
Molecular cloning and nucleotide sequencing of a novel aminoglycoside 6'-N-acetyltransferase gene from an R-plasmid of Salmonella typhimurium S24 isolated in Taiwan.
Microbiology and immunology - 1 Jan 1992
Peng C F, Chang S F
Abstract excerpt
A conjugative aminoglycoside resistance plasmid pST2 has been isolated from Escherichia coli K-12 14R525, which was mated with a clinical isolate of Salmonella typhimurium S24. A novel resistance gene of aminoglycoside 6'-N-acetyltransferase[AAC(6')] was cloned from plasmid pST2 on a 1,393 kilobase (kb) of SphI-SalI fragment into vector pACYC184 and pUC18. This novel AAC(6') gene in plasmid pST2 acetylated...
Topics
- Acetyltransferases
- Amino Acid Sequence
- Aminoglycosides
- Base Sequence
- Cloning, Molecular
- Disease Outbreaks
- Drug Resistance, Microbial
- Molecular Sequence Data
- Phenotype
- R Factors
- Salmonella Infections