Article
Insertion sequence ISEcp1-like element connected with a novel aph(2'') allele [aph(2'')-Ie] conferring high-level gentamicin resistance and a novel streptomycin adenylyltransferase gene in Enterococcus.
Journal of medical microbiology - 1 Nov 2006
Chen Ya-Gang, Qu Ting-Ting, Yu Yun-Song, Zhou Jian-Ying, Li Lan-Juan
Abstract excerpt
Enterococcus casseliflavus HZ95 is an enterococcus with high-level resistance to aminoglycosides. Nine genes responsible for high-level aminoglycoside resistance, including aac(6')-Ie-aph(2'')-Ia, aph(2'')-Ib, aph(2'')-Ic, aph(2'')-Id, aph(3')-IIIa, aac(6')-Ii, ant(3')-Ia, ant(4')-Ia and ant(6')-Ia, were not detected in HZ95. An 8 kb fragment from unconjugative plasmids of HZ95 was cloned, and expressed...
Topics
- Alleles
- Amino Acid Sequence
- Anti-Bacterial Agents
- Base Sequence
- Cloning, Molecular
- Conjugation, Genetic
- Cross Infection
- DNA Transposable Elements
- DNA, Bacterial
- Drug Resistance, Bacterial
- Enterococcus
- Gentamicins
- Humans