Article
Structure analysis of transposons carrying the aac(6')-aph(2″) gene in Enterococcus faecalis isolated in Beijing, China, and comparison of their transfer efficiency.
International journal of antimicrobial agents - 1 Dec 2018
Zhang Jian-Mei, Wang Qing, Han Tong-Yan, Liu Jian-Hua, Hu Xin-Xin, Qiao Feng, Yang Xin-Yi, Li Cong-Ran, You Xue-Fu
Abstract excerpt
Transfer of aac(6')-aph(2″) transposons mediating high-level gentamicin resistance (HLGR) in Enterococcus faecalis is a serious problem in the clinic. However, factors affecting the transfer of aac(6')-aph(2″) have not yet been elucidated. The current study aimed to examine the genetic and molecular basis of HLGR in E. faecalis strains isolated in Beijing (China) and to clarify the relationship between transfer...
Topics
- Acetyltransferases
- Anti-Bacterial Agents
- Beijing
- Chromosome Mapping
- Conjugation, Genetic
- DNA Transposable Elements
- Drug Resistance, Bacterial
- Enterococcus faecalis
- Gene Transfer, Horizontal
- Genetic Variation
- Gentamicins
- Gram-Positive Bacterial Infections