Article
Mutational analysis of a putative polyphosphoinositide binding site in phospholipase C-beta 2.
FEBS letters - 29 May 1995
Simões A P, Camps M, Schnabel P, Gierschik P
Abstract excerpt
The phosphatidylinositol 4,5-bisphosphate (PtdIns-P2)-regulated actin-binding protein gelsolin and most phosphoinositide-specific phospholipases C (PLCs) comprise a basic amino acid motif ((K/R)xxxKxK(K/R); x denotes any amino acid) which was previously suggested to represent a PtdInsP2-binding s...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Cloning, Molecular
- DNA Mutational Analysis
- DNA Primers
- DNA, Complementary
- Escherichia coli
- Gene Expression
- Genetic Variation
- Humans
- Molecular Sequence Data