Structural requirements of phosphatidylinositol-specific phospholipase C delta 1 for enzyme activity.

doi:10.1111/j.1432-1033.1993.tb17767.x

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Article

Structural requirements of phosphatidylinositol-specific phospholipase C delta 1 for enzyme activity.

European journal of biochemistry - 1 Apr 1993

Ellis M V, Carne A, Katan M

Abstract excerpt

Phosphatidylinositol-specific phospholipase C delta 1 isozyme of phosphoinositol-specific phospholipase C has been used for studies of structural requirements for the catalytic function. The enzyme was expressed in a bacterial system and purified to homogeneity. Using a combination of deletion mu...

Topics

Amino Acid Sequence
Gene Expression
Hydrolysis
Molecular Sequence Data
Mutation
Peptide Fragments
Phosphatidylinositol Diacylglycerol-Lyase
Phosphoinositide Phospholipase C
Phosphoric Diester Hydrolases
Protein Conformation

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