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Article

Allele-specific mutations involved in the pathogenesis of endemic gallbladder carcinoma in Chile.

Cancer research - 15 Jun 1995

Wistuba I I, Sugio K, Hung J, Kishimoto Y, Virmani A K, Roa I, Albores-Saavedra J, Gazdar A F

Abstract excerpt

Although gallbladder carcinoma is one of the most frequent neoplasms in Chile, there is limited information about the molecular changes involved in its pathogenesis. We investigated the incidence of ras gene mutations and loss of heterozygosity (LOH) at the following genes/loci: p53, DCC, rb, 5q 3p, 8p, and 9p. We precisely microdissected 194 relevant areas from paraffin-embedded microslides from 25 gallbladder...

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Source

Identifiers

PMID: 7780959

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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