Genetic alterations involved in the development of gallbladder carcinomas from Greek patients.

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Article

Genetic alterations involved in the development of gallbladder carcinomas from Greek patients.

Hepato-gastroenterology - 1 Jan 2000

Saetta A, Lazaris A C, Michalopoulos N V, Davaris P S

Abstract excerpt

BACKGROUND/AIMS: The genetic pathways of gallbladder cancer are not yet well defined since the contribution of genetic abnormalities clarified in other organs remains questionable. METHODOLOGY: We investigated a group of 22 gallbladder carcinomas from Greek patients with regard to p53 mutations, bax and TGF-beta RII alterations--as indicators of microsatellite instability. The findings were correlated to the...

Topics

Adenocarcinoma
Adenocarcinoma, Papillary
Adult
Aged
Aged, 80 and over
Cell Transformation, Neoplastic
Female
Gallbladder
Gallbladder Neoplasms
Gene Expression Regulation, Neoplastic
Greece
Humans
Male
Middle Aged

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Staging

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 11677947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.