Article
Genetic alterations involved in the development of gallbladder carcinomas from Greek patients.
Hepato-gastroenterology - 1 Jan 2000
Saetta A, Lazaris A C, Michalopoulos N V, Davaris P S
Abstract excerpt
BACKGROUND/AIMS: The genetic pathways of gallbladder cancer are not yet well defined since the contribution of genetic abnormalities clarified in other organs remains questionable. METHODOLOGY: We investigated a group of 22 gallbladder carcinomas from Greek patients with regard to p53 mutations, bax and TGF-beta RII alterations--as indicators of microsatellite instability. The findings were correlated to the...
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